The world we see that seems so insane is the result of a belief system that is not working. To perceive the world differently we must be willing to change our belief system let the past slip away expand our sense of now and dissolve the fear in our minds.
Your 40s are a major trough. About the age of 50 feelings of satisfaction begin to rebound and keep rising into your 50s 60s and 70s with health being a major factor.